Diastereoselective synthesis of nitroso acetals from (S,E)-γ-aminated nitroalkenes via multicomponent [4 + 2]/[3 + 2] cycloadditions promoted by LiCl or LiClO₄

• Leandro Lara de Carvalho,
• Robert Alan Burrow and
• Vera Lúcia Patrocinio Pereira

Beilstein J. Org. Chem. 2013, 9, 838–845, doi:10.3762/bjoc.9.96

• diffraction experiment. Keywords: chiral heterodiene; hetero-Diels–Alder reaction; pyrrolizidin-3-one; solvent effect; tandem reaction; Introduction Conjugated nitroalkenes play an important role in cycloaddition reactions providing useful nitrogenated cycloadducts with varied synthetic applications (Scheme